What clinical feature is more often associated with essential thrombocytosis than with the other chronic myeloproliferative disorders?
a. Splenomegaly
b. Bleeding and thrombosis
c. Fatigue
d. Infections
ANS: B
Bleeding and thromboembolic complications are characteristic of essential thrombocytosis. Patients with polycythemia vera who are treated only with phlebotomy are at increased risk for bleeding and thrombosis, but it is otherwise not characteristic of polycythemia vera. Splenomegaly is seen in all the myeloproliferative disorders, as are fatigue and infections.
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