Which of the following is false about the optimal technique for using a small-volume jet nebulizer (SVN) for aerosol drug delivery?
a. SVNs are less technique- and de-vice-dependent.
b. Slow inspiration improves SVN aerosol deposition.
c. Deep breathing or breath-holding im-proves SVN deposition.
d. Use of a mouthpiece or mask provides similar results.
ANS: C
Use of an SVN is less technique- and device-dependent than use of a pressurized metered dose inhaler or dry powder inhaler delivery system. Slow inspiratory flow does optimize SVN aerosol deposition. However, deep breathing and breath-holding during SVN therapy do little to en-hance deposition over normal tidal breathing. Because the nose is an efficient filter of particles larger than 5 mm, many clinicians prefer not to use a mask for SVN therapy. As long as the pa-tient is mouth-breathing, there is little difference in clinical response between therapy given by mouthpiece and that given by mask.
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