All of the following statements about anaphylactoid transfusion reactions are true except

a. They are serious and life-threatening
b. They are triggered by IgE class antibodies that release mediators from mast cells
c. They can be caused by reaction between a protein allergen and its corresponding antibody
d. They can be caused by IgA in the transfused blood product reacting with anti-IgA in the patient's plasma

Answer: a

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