Explain the risks associated with the concomitant use of local anesthetic drugs and cocaine

What will be an ideal response?

Cocaine is a strong CNS depressant and local anesthetics can compound any existing CNS depression. Cocaine is also a vasoconstrictor. Administration of other vasoconstrictors in addition to cocaine significantly increases the risk of hypertensive crisis, stroke, or myocardial infarction. Do notadminister local anesthetics with vasoconstrictors for 24 hours after cocaine use and patients should be monitored for local anesthetic drug overdose.