Which of the following is true about iron absorption?
a. It occurs primarily in the stomach.
b. Phytates and tannates enhance its absorption.
c. Ascorbic acid inhibits its absorption.
d. It must be in ferrous form for absorption.
ANS: D
Iron must be in the ferrous (divalent) state for absorption, which occurs primarily in the duodenum and upper jejunum. Any dietary iron that is in the ferric form is reduced to the soluble ferrous form by a duodenum-specific cytochrome b–like protein. Ascorbic acid enhances absorption, whereas phytates and tannates inhibit absorption.
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