What treatment for patients with COPD has been shown to improve long-term survival?
a. Bronchodilators
b. Corticosteroids
c. Mechanical ventilation
d. Oxygen
ANS: D
Among the available treatments for COPD, supplemental oxygen is important because, like smoking cessation and lung-volume reduction surgery in selected individuals (see below), it can prolong survival. Box 23-2 reviews the indications for supplemental oxygen, and Figure 23-6 shows the results of the American Nocturnal Oxygen Therapy Trial and the British Medical Re-search Council Trial of Domiciliary Oxygen, 1980-1981. Survival was improved when eligible patients used supplemental oxygen for as close to 24 hr as possible and that survival improved less for those using oxygen only 15 hr/day.
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