What important function does 2,3-BPG perform?
a. Maintains iron in the hemoglobin molecule in the ferrous state
b. Prevents oxidative injury to the red cell
c. Facilitates the delivery of oxygen to tissue
d. Aids in the exchange of membrane lipids with lipids in plasma
ANS: C
2,3-BPG plays a critical role in the effective transport of oxygen to tissue. It is produced via a shunt off the EMP. Elevations in 2,3-BPG are seen in a number of situations such as anemia; they result in more effective delivery of oxygen to tissue. It has no role in the other functions listed.
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