What is the major advantage and disadvantage of both mainstream and sidestream capnography?

What will be an ideal response?

The major advantage of mainstream analysis is the fast response time between actual CO2 sampling and the display update. The disadvantage of the mainstream adapter is its excessive weight on the endotracheal tube as well as the additional deadspace in the ventilator/ patient circuit. The major advantage with sidestream analysis is the ease of handling and it can be attached to other patient devices (e.g., cannula, mask). The major disadvantage is that with periodic aspiration of air samples, secretions and water can be drawn into the sampling tube and cause an occlusion.