Explain how hematopoiesis uses autocrine, paracrine, and juxtacrine signaling. Choose one and provide an example of signaling through that pathway
What will be an ideal response?
Answer: Autocrine signaling: produced by and act on the same cell. Example: Rarely seen; T-cells and IL-2.
Paracrine signaling: produced by and act on adjacent cells. Example: progenitors and precursors adjacent to the BM stroma.
Juxtacrine signaling: The cytokine remains membrane-bound, which requires interaction between membrane and membrane receptors to achieve the desired effect. Example: stem cells and SCF or FL.
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Which of the following is the most appropriate action when the medical assistant is taking the medical history?
a. Ask the patient whether there are any questions. b. Use medical jargon when possible. c. Be firm and inflexible. d. Ask intimate questions right away to get them over with.
Define the underlined terms in the following case study. A member of the columbiforme family was presented to the clinic with an apparent habit of feather picking. The attending veterinarian noted absence of retrices as well as remiges. In addition, the veterinarian documented damage to the bird's uropygial gland