An antiemetic that potentiates the depressant effects on the CNS of narcotics, sedatives or hypnotics, and alcohol and no longer used commonly by emergency medical services is:
a. Ondansetron (Zofran)
b. Dolasetron (Anzemet)
c. Promethazine (Phenergan)
d. Prochlorperazine (Compazine)
c
Rationale: a. Zofran is a serotonin antagonist having less effect on CNS depressants.
b. Dolastron is a serotonin antagonist having less effect on CNS depression.
c. Correct.
d. Prochlorperazine has weak anticholinergic properties having less effect on CNS depression.
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