The phase of drug testing that determines the pharmacokinetics, toxicity, and safe dose in humans is:
a. Phase one
b. Phase two
c. Phase three
d. Phase four
a
Rationale: a. The primary purpose of phase one testing is to determine the pharmacokinetics, toxicity, and safe dose in humans.
b. Tthe primary purpose of phase ttwo testing is to find the therapeutic medication level and watch carefully for toxic and side effects.
c. The primary purpose of phase threeItesting is to refine the usual therapeutic dose and to collect relevant data on side effects.
d. The primary purpose of phase Ifour testing involves postmarketing analysis during conditional approval.
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