Which of the following statements is true concerning replacement of hormones in postmenopausal women?

a. When estrogen is used alone, it is referred to as hormonal replacement therapy (HRT).
b. Progesterone is usually combined with estrogen in women with a uterus.
c. When estrogen is combined with progesterone, it is referred to as estrogen replacement therapy.
d. An adverse effect of estrogen therapy is depression.
e. Patients taking estrogen may complain of xerostomia.

b. When estrogen is used alone, it is called estrogen replacement therapy (ERT), and when estrogen is used in combination progestins it is referred to as hormonal replacement therapy (HRT). In women without a hysterectomy (with a uterus), progesterone should be added to the estrogen, which may reduce the incidence of endometrial hyperplasia.