What is believed to be the cause for acute immune thrombocytopenia purpura in children?

a. Development of a platelet-specific autoantibody
b. Development of a white cell autoantibody that cross-reacts with platelet membrane antigens
c. Development of an allogeneic antibody after transfusion of random allogeneic platelets
d. Nonspecific binding of immune complexes to the platelet membrane after a viral illness

ANS: D
Acute immune thrombocytopenia purpura in children often follows a viral illness. This suggest that some children produce antibodies and immune complexes against viral antigens and that platelet destruction may result from their binding to the platelet membrane.

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