Long-term potentiation (LTP) can be produced in areas CA1 and CA3 of the hippocampus. Which of the following is strong evidence that non-NMDA mechanisms can mediate LTP?

a. NMDA receptors are sparse in area CA3.
b. AMPA blocks the LTP produced in area CA1.
c. NMDA receptors are sparse in area CA1.
d. AP5 blocks the LTP produced in area CA3.
e. AMPA agonists block the LTP produced in area CA3.

Answer: a. NMDA receptors are sparse in area CA3.

Psychology

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